Biotechnology is a set of multidisciplinary activities using cell and molecule-based processes from biological systems, such as live and bio-derived organisms (microorganisms, cells, and molecules), to develop technology and products that benefit healthcare, environment, agriculture, livestock, and infrastructure industries.
In the healthcare industry, Cristália builds on integrated knowledge in biochemistry, microbiology, genetics, engineering, chemistry, technology information, among others to develop products and drugs aimed to humankind's health and well-being.
Cristália has two Biotechnology plants certified by ANVISA (National Sanitary Surveillance Agency), launched in 2013 and 2014, and operational for the manufacturing of Biological Active Pharmaceutical Ingredients (APIs). The launching of these plants reflects a milestone both for Cristália and for Brazil, consolidating the company as an industry benchmark.
Cristália was the first Brazilian pharmaceutical company to be granted with the Good Manufacturing Practices Certification (GMPC) for the manufacturing of Biological APIs.
Cristália has been already manufacturing its somatropin – or Human Growth Hormone – in its Biotechnology plant. This drug is mostly prescribed for treating children with growth deficiency syndrome.
In the Biotechnology, Anaerobics plant, the Active Pharmaceutical Ingredient (API) animal-free collagenase is manufactured. This product is used in the manufacturing of Kollagenase ointment to treat wounds, ulcers and burns.
Such successful background in Biotechnology at Cristália is the result of the efforts of a team of expert colleagues. Hard work, study, and dedication from finding microorganisms (either genetically modified or deriving from biodiversity), process development and manufacturing, design, building, and startup of manufacturing plants to commercial production.
Biotechnology also counts on Cristália's structure support, including quality control, quality assurance, warehouse, new products development, maintenance, information technology, and the pharmaceutical plant for getting to the finished products.
Our Biotechnology plants have production platforms based on bacteria and animal cells.
The enzyme collagenase is a product derived from an anaerobic bacteria in culture extracted from Brazilian biodiversity. Somatropin is a recombinant protein derived from a genetically modified bacteria.