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Laboratório Cristália has ten pharmaceutical plants, three of them located at Itapira Industrial Complex, in the state of São Paulo, one in São Paulo city, one in Cotia (SP), one in Pouso Alegre (MG), two in Rio de Janeiro, one in Cosmópolis (SP), and one in Argentina.

While the pharmaceutical manufacturing plants in Itapira making up Site I (Pharmaceutical I, Pharmaceutical II, and Oncology Pharmaceutical) are responsible for the manufacturing of solid and semi-solid, oral solutions, eyedrops, and injectables, the manufacturing plant located in São Paulo is responsible for the manufacturing of solutions and lyophilized products for hospital use.

The plant located in Cotia (Latinofarma) is exclusively designed to the manufacturing of Ophthalmic products. Also, parenteral solutions (Pouso Alegre), cosmetics and repellents (Cosmópolis), inhaled antibiotics and anesthetics (Rio de Janeiro), and injectable oncology drugs (Argentina) are manufactured.


Quadrupled production


Pharmaceutical plants I and II are housed at Itapira Industrial Park with a total building area of 51,000 m2. The first plant was opened in 1972, on a 16,000 m2 area, and the second one in 2010, with a building area of 35,000 m².

The pharmaceutical unit II, opened in 2010, has been designed to increase company's production by four fold, in order to meet market demands. With state-of-the-art equipment in place, over 100 million dollars have been invested in the plant in terms of structure and equipment assuring that raw materials and products are transferred with the utmost safety to finished products, colleagues, and the environment. The Oncology Pharmaceutical plant, previously known as Cytostactics, was launched in 2013, and is responsible for the manufacturing of drugs for cancer.

Established in Cotia, on an area of more than 20,000 m², the Ophthalmology plant has a manufacturing capacity of about 3.5 million units a month, including ophthalmic corticosteroids, antibiotics and antiseptics, but the main product is artificial tears.

In Pouso Alegre(MG), Cristália counts on a manufacturing plant totally dedicated to Hospital products. On an area of 25 thousand m², the state-of-the-art plant has a built area of 15 thousand m², where high-volume parenteral solutions in vials and pouches are manufactured, including saline, glucose, and glucosaline solutions. The pouch line also encompasses important hospital-use drugs, such as Levofloxacin, Fluconazole, and Linezolid.

Primary traceability


Cristália's Pharmaceutical plant has been the first in the country to provide primary traceability for hospital-related products. The whole portfolio of injectables (both fluids and lyophilized products), solids (tablets, lozenges, and capsules), and semi-solids (creams and ointments) designed for hospital use bear an individual DataMatrix code.

Hospital pharmacies can more easily and safely check the active substances, product expiration dates, and manufacturing batches by using an optical scanner.

Learn more about Cristália's traceability project using Datamatrix code at: Datamatrix coding.